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Finally, transcriptomic analyses were performed on key metabolic brain regions including the dorsal vagal complex (DVC), LPBN, and mediobasal hypothalamus (MBH), after 21 days of treatment

Large randomized controlled trials in humans are absent, so clinical efficacy claims lack robust evidence

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The amylin component contributes to blood sugar control through glucagon suppression and delayed gastric emptying, both of which reduce postprandial glucose spikes